Document Detail


Method for studying arterial wave transmission effects on left ventricular function.
MedLine Citation:
PMID:  2000959     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A technique for studying the real-time effects of arterial wave reflections on the performance of the isolated left ventricle was investigated. Real-time arterial loading of an isolated ferret heart with an asymmetric T-tube wave transmission model was obtained with the use of a multiprocessor computer control system and a volume control linear motor pump. The multiprocessor computer system was programmed to compute the instantaneous aortic flow from the instantaneous ventricular pressure. The time integral of the flow was used as a command to the linear motor pump to control the instantaneous ventricular volume. This loading system allowed the imposition of a wide variety of vascular impedances on the ventricle by changing the parameters of the asymmetric T-tube model.
Authors:
R D Kirkpatrick; K B Campbell; D L Bell; H Taheri
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  260     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-04-11     Completed Date:  1991-04-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  H1003-12     Citation Subset:  IM    
Affiliation:
Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Washington State University, Pullman 99164-6520.
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MeSH Terms
Descriptor/Qualifier:
Animals
Arteries / physiology*
Cardiology / instrumentation
Computers
Equipment Design
Ferrets
Male
Models, Cardiovascular*
Rats
Time Factors
Vascular Resistance
Ventricular Function, Left / physiology*
Grant Support
ID/Acronym/Agency:
HL-21462/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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