| Methemoglobinemia from overdose of phenazopyridine hydrochloride. | |
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MedLine Citation:
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PMID: 7362105 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of severe methemoglobinemia and hemolytic anemia following ingestion of 5.6 gm of phenazopyridine with suicidal intent by a 16-year-old woman was successfully treated with intravenous methylene blue. Methemoglobinemia was suspected in this patient because of her intense central cyanosis, chocolate-colored blood, and minimal dyspnea. The patient's peripheral blood smear exhibited "bite cells." To the best of our knowledge, this is only the third such case reported in the literature. The pathophysiology, diagnosis, and therapy are reviewed. |
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Authors:
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R C Zimmerman; E D Green; W H Ghurabi; D P Colohan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Annals of emergency medicine Volume: 9 ISSN: 0196-0644 ISO Abbreviation: Ann Emerg Med Publication Date: 1980 Mar |
Date Detail:
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Created Date: 1980-05-14 Completed Date: 1980-05-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8002646 Medline TA: Ann Emerg Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 147-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Aminopyridines / poisoning* Female Humans Methemoglobin / analysis Methemoglobinemia / chemically induced*, drug therapy Methylene Blue / administration & dosage* Phenazopyridine / poisoning* Suicide, Attempted |
| Chemical | |
Reg. No./Substance:
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0/Aminopyridines; 61-73-4/Methylene Blue; 9008-37-1/Methemoglobin; 94-78-0/Phenazopyridine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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