Document Detail

Methanol-induced vision loss.
MedLine Citation:
PMID:  9479937     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Accidental or purposeful consumption of small amounts of methanol can lead to severe vision loss or death. Vision loss is rapid--usually symmetric--and most often affects the central (or centrocecal) visual field, although peripheral visual loss may occur as well. Fixed, dilated pupils and optic atrophy, with or without excavation, are the most common findings in persons with methanol-induced vision loss. CASE REPORT: A 35-year-old man was examined after consuming methanol in the form of windshield wiper fluid. Despite relatively rapid treatment for the patient's methanol poisoning and associated metabolic acidosis, permanent, severe vision loss with associated optic neuropathy developed. Because of the finding of fixed, dilated pupils on the patient's initial presentation, severe vision loss was an expected result for this patient. CONCLUSIONS: Prompt recognition and proper medical treatment are the main factors in successful management of methanol poisoning. Even if proper and timely medical response is achieved, however, the patient may still experience permanent neurologic sequelae or death. Notably, pupillary status may provide the best prognostic information for both morbidity and mortality.
M Sullivan-Mee; K Solis
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Optometric Association     Volume:  69     ISSN:  0003-0244     ISO Abbreviation:  J Am Optom Assoc     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-03-16     Completed Date:  1998-03-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505575     Medline TA:  J Am Optom Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  57-65     Citation Subset:  IM    
U.S. Indian Health Service, Chinle Public Health Service Hospital, Arizona, USA.
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MeSH Terms
Acidosis / chemically induced*,  pathology
Follow-Up Studies
Fundus Oculi
Methanol / poisoning*
Optic Nerve Diseases / chemically induced*,  pathology
Pupil Disorders / chemically induced*,  pathology
Solvents / poisoning*
Vision, Low / chemically induced*,  pathology
Visual Acuity
Reg. No./Substance:
0/Solvents; 67-56-1/Methanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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