Document Detail


Methane as fuel for anaerobic microorganisms.
MedLine Citation:
PMID:  18096853     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Methane has long been known to be used as a carbon and energy source by some aerobic alpha- and delta-proteobacteria. In these organisms the metabolism of methane starts with its oxidation with O(2) to methanol, a reaction catalyzed by a monooxygenase and therefore restricted to the aerobic world. Methane has recently been shown to also fuel the growth of anaerobic microorganisms. The oxidation of methane with sulfate and with nitrate have been reported, but the mechanisms of anaerobic methane oxidation still remains elusive. Sulfate-dependent methane oxidation is catalyzed by methanotrophic archaea, which are related to the Methanosarcinales and which grow in close association with sulfate-reducing delta-proteobacteria. There is evidence that anaerobic methane oxidation with sulfate proceeds at least in part via reversed methanogenesis involving the nickel enzyme methyl-coenzyme M reductase for methane activation, which under standard conditions is an endergonic reaction, and thus inherently slow. Methane oxidation coupled to denitrification is mediated by bacteria belonging to a novel phylum and does not involve methyl-coenzyme M reductase. The first step in methane oxidation is most likely the exergonic formation of 2-methylsuccinate from fumarate and methane catalyzed by a glycine-radical enzyme.
Authors:
Rudolf K Thauer; Seigo Shima
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-12-20
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  1125     ISSN:  0077-8923     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-04-01     Completed Date:  2008-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  158-70     Citation Subset:  IM    
Affiliation:
Max Planck Institute for Terrestrial Microbiology, Karl-von-Frisch-Strasse, D-35043 Marburg, Germany. thauer@mpi-marburg.mpg.de
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MeSH Terms
Descriptor/Qualifier:
Alkanes / metabolism
Anaerobiosis
Archaea / enzymology,  metabolism*
Bacteria / metabolism*
Bacteria, Anaerobic / metabolism*
Ethane / metabolism
Hydrogen Sulfide / metabolism
Methane / metabolism*
Methanosarcina / metabolism*
Oxidation-Reduction
Oxidoreductases / metabolism
Propane / metabolism
Sulfates / metabolism
Chemical
Reg. No./Substance:
0/Alkanes; 0/Sulfates; 74-82-8/Methane; 74-84-0/Ethane; 74-98-6/Propane; 7783-06-4/Hydrogen Sulfide; EC 1.-/Oxidoreductases; EC 2.8.4.1/methyl coenzyme M reductase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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