Document Detail


Methadone-induced bilateral severe sensorineural hearing loss.
MedLine Citation:
PMID:  24051235     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Methadone, a long-acting opiate agonist, and naltrexone, an opiate receptor antagonist, are both commonly used to treat patients with morphine and heroin addiction. We present a rare case of methadone-induced persistent bilateral sensorineural hearing loss (SNHL) after chronic naltrexone use and review opioid-induced hearing loss in the literature. Methadone-induced hearing loss has been described previously described in the literature with all reported cases recovering functional hearing. This is the first description of persistent bilateral severe SNHL following methadone ingestion. We propose opiate receptor sensitization from prolonged naltrexone use as a predisposing factor for methadone-induced irreversible cochlear injury.
Authors:
Nopawan Vorasubin; Audrey P Calzada; Akira Ishiyama
Related Documents :
9468255 - Characteristic pancreatic duct appearance in autoimmune chronic pancreatitis: a case re...
8470845 - Acute urinary retention: an unusual presentation of appendiceal abscess.
16564305 - Acute intraoperative malfunction of aortic valve due to surgical glue.
22856445 - Misdiagnosis of diaphragmatic rupture in a trauma setting.
11964685 - Workplace irritant exposures: do they produce true occupational asthma?
15746465 - Study of the relationship between social deprivation and outcome after stroke.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-9-16
Journal Detail:
Title:  American journal of otolaryngology     Volume:  -     ISSN:  1532-818X     ISO Abbreviation:  Am J Otolaryngol     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-9-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000029     Medline TA:  Am J Otolaryngol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013.
Affiliation:
Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address: nvorasubin@mednet.ucla.edu.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Utility of positron emission tomography/computed tomography for nodal staging of cutaneous squamous ...
Next Document:  Nasopharyngeal pleomorphic adenoma presenting as otitis media with effusion: Case report and literat...