Document Detail


Metformin: diamonds are forever.
MedLine Citation:
PMID:  19678795     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Metformin has now been established as the drug of choice for the first-line management of type 2 diabetes mellitus. It reduces insulin resistance, improves glycaemic control, and can be safely combined with other classes of oral hypoglycaemic agents. Equally important, metformin has been shown to have a significant beneficial effect on cardiovascular morbidity. Moreover, this agent acts favourably on blood pressure, lipids, haemostasis and other features of the metabolic syndrome. Metformin also contributes to weight reduction and diabetes prevention.
Authors:
N Papanas; E Maltezos; D P Mikhailidis
Related Documents :
8453955 - Metformin for obese, insulin-treated diabetic patients: improvement in glycaemic contro...
12404195 - Effects of berberine on glucose metabolism in vitro.
22780885 - Therapeutic implications of vitamin d and calcium in overweight women with polycystic o...
20107105 - Effects of exenatide plus rosiglitazone on beta-cell function and insulin sensitivity i...
18491075 - The central carbohydrate metabolism of the hyperthermophilic crenarchaeote thermoproteu...
17121785 - The haemodynamic and metabolic effects of hypertonic-glucose and amino-acid-based perit...
Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  10     ISSN:  1744-7666     ISO Abbreviation:  Expert Opin Pharmacother     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-18     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  England    
Other Details:
Languages:  eng     Pagination:  2395-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Blood Glucose / drug effects
Cardiovascular Diseases / etiology,  prevention & control
Clinical Trials as Topic
Diabetes Mellitus, Type 2 / complications,  drug therapy*
Humans
Hypoglycemic Agents / adverse effects,  pharmacology,  therapeutic use*
Insulin Resistance
Metformin / adverse effects,  pharmacology,  therapeutic use*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Hypoglycemic Agents; 657-24-9/Metformin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  New antiretroviral drugs: a review of the efficacy, safety, pharmacokinetics, and resistance profile...
Next Document:  Discontinued drugs in 2008: endocrine and metabolic.