| Metformin-associated lactic acidosis. | |
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MedLine Citation:
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PMID: 11267815 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 1995, the oral antihyperglycemic agent, metformin, was introduced in the United States for treating diabetes mellitus. Rare cases of metformin-associated lactic acidosis caused by the accumulation of the drug in patients with renal dysfunction have been described, although a detailed time course of the resulting metabolic derangements has not been reported. A case of metformin-associated lactic acidosis is presented along with key serial laboratory abnormalities observed during the treatment phase. The patient made a complete recovery following therapy with hemodialysis and supportive care. |
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Authors:
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J A Kruse |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of emergency medicine Volume: 20 ISSN: 0736-4679 ISO Abbreviation: J Emerg Med Publication Date: 2001 Apr |
Date Detail:
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Created Date: 2001-03-27 Completed Date: 2001-05-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8412174 Medline TA: J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 267-72 Citation Subset: IM |
Affiliation:
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Detroit Receiving Hospital and Wayne State University School of Medicine, Detroit, Michigan 48201, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acidosis, Lactic
/
chemically induced*,
physiopathology,
therapy Aged Female Humans Hypoglycemic Agents / adverse effects* Metformin / adverse effects* Renal Dialysis |
| Chemical | |
Reg. No./Substance:
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0/Hypoglycemic Agents; 657-24-9/Metformin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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