Document Detail

Metastatic uterine leiomyosarcoma presenting as a breast lump.
MedLine Citation:
PMID:  19184604     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: It is uncommon to encounter a breast metastasis from an extramammary malignancy and even rarer from a uterine leiomyosarcoma.
AIMS: We describe the third case report in the medical literature of a breast metastasis from a uterine leiomyosarcoma.
METHODS: We report the management of a 56-year-old patient who presented with a breast lump 3 years after hysterectomy for a fibroid uterus. We conducted a literature review of breast leiomyosarcomas.
RESULTS: The excision of the breast mass revealed a low-grade leiomyosarcoma. Radiographic examinations demonstrated metastases to the lung, liver, pelvis and bone. Retrospective pathology review of her uterus identified a small focus of leiomyosarcoma. She received chemotherapy and palliative radiotherapy but passed away within few months.
CONCLUSION: Metastasis to the breast from a non-breast primary is generally a sign of disseminated disease and; thus, a poor prognostic indicator.
S Sibartie; J O Larkin; G Lee; J Fitzgibbon; S O'Reilly; D Richardson
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Publication Detail:
Type:  Journal Article     Date:  2009-01-31
Journal Detail:
Title:  Irish journal of medical science     Volume:  180     ISSN:  1863-4362     ISO Abbreviation:  Ir J Med Sci     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-10-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806864     Medline TA:  Ir J Med Sci     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  889-91     Citation Subset:  IM    
Department of Surgery, South Infirmary Victoria University Hospital, Cork, Ireland,
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