| Metastatic squamous cell carcinoma presenting as diffuse and punctate cervical lymph node calcifications: sonographic features and utility of sonographically guided fine-needle aspiration biopsy. | |
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MedLine Citation:
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PMID: 19933485 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this series was to show the sonographic appearance of calcified cervical lymph nodes and the utility of sonographically guided fine-needle aspiration biopsy (FNAB) in the setting of metastatic squamous cell carcinoma (SCC). METHODS: Two cases of confirmed metastatic SCC to cervical lymph nodes were identified. Sonography and sonographically guided FNAB were performed in both cases with positron emission tomography (PET)/computed tomography (CT) correlation. RESULTS: In case 1, sonography identified a diffusely calcified, avascular cervical lymph node. Positron emission tomography/CT suggested granulomatous disease as a cause for hypermetabolism; however, sonographically guided FNAB identified metastatic SCC. In the second case, FNAB initially performed without sonographic guidance did not show malignancy. Subsequent FNAB with sonographic guidance identified an abnormal cervical lymph node with focal calcifications and internal color Doppler flow. Metastatic SCC was diagnosed on histopathologic examination. Subsequent PET/CT confirmed multiple punctate calcifications in a hypermetabolic lymph node. CONCLUSIONS: Calcifications in cervical lymph nodes from metastatic SCC are very rare. These 2 cases show the variable sonographic appearances and the utility of sonographically guided FNAB in establishing the correct diagnosis. |
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Authors:
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Lewis K Shin; Nancy J Fischbein; Michael J Kaplan; R Brooke Jeffrey |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine Volume: 28 ISSN: 1550-9613 ISO Abbreviation: J Ultrasound Med Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-11-25 Completed Date: 2010-02-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211547 Medline TA: J Ultrasound Med Country: United States |
Other Details:
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Languages: eng Pagination: 1703-7 Citation Subset: IM |
Affiliation:
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Veterans Affairs Palo Alto Health Care System, Palo Alto and Department of Radiology, Stanford University School of Medicine, Stanford, California, USA. lshin@stanford.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy, Fine-Needle
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methods* Calcinosis / pathology*, ultrasonography Carcinoma, Squamous Cell / pathology*, secondary*, ultrasonography Female Head and Neck Neoplasms / pathology*, ultrasonography Humans Lymphatic Diseases / pathology*, ultrasonography Lymphatic Metastasis Male Middle Aged Neck Ultrasonography, Interventional / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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