Document Detail

Metastatic renal clear cell carcinoma mimicking stage IV lung cancer.
MedLine Citation:
PMID:  14620276     Owner:  NLM     Status:  MEDLINE    
We present a 63-year-old man who was investigated for a lesion in the apex of the left lung and a coexisting osteolytic lesion in the right major trochanter. FNA of the thoracic mass was suggestive for malignancy yet not diagnostic regarding the tumor type and the site of the primary tumor. A diagnosis of a stage IV lung cancer was favored and he underwent a left exploratory thoracotomy in view to resect the primary tumor. An extrapulmonary mass localized to the pleura not involving the ipsilateral lung was disclosed. Multiple biopsies revealed metastatic clear cell RCC. A 5 x 7 cm left renal tumor was revealed in a postoperative abdominal CT scan. He was treated with combination of interferon A and vinblastin followed by radical nephrectomy. Twenty-four months after the diagnosis he is alive without evidence of local or distant recurrence. Pleural metastases from RCC are mainly presented as malignant pleural effusions. Thoracic metastatic lesions localized to the pleura, forming solitary or multiple mass(es) have been rarely reported. We review the literature regarding this rare clinical manifestation of the disease and we discuss diagnostic and therapeutic options.
J Griniatsos; P O Michail; C Menenakos; D Hatzianastasiou; C Koufos; E Bastounis
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  International urology and nephrology     Volume:  35     ISSN:  0301-1623     ISO Abbreviation:  Int Urol Nephrol     Publication Date:  2003  
Date Detail:
Created Date:  2003-11-17     Completed Date:  2004-02-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0262521     Medline TA:  Int Urol Nephrol     Country:  Hungary    
Other Details:
Languages:  eng     Pagination:  15-7     Citation Subset:  IM    
Surgical Department, University of Athens, Laiko Hospital, Athens, 115-27, Greece.
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MeSH Terms
Adenocarcinoma, Clear Cell / pathology*,  secondary*
Diagnosis, Differential
Kidney Neoplasms / pathology*
Lung Neoplasms / pathology*,  secondary*
Middle Aged
Neoplasm Staging

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