Document Detail

Metastatic paraganglioma of the spine: Case report and review of the literature.
MedLine Citation:
PMID:  23398849     Owner:  NLM     Status:  Publisher    
Paragangliomas are relatively rare tumors, accounting for only about 0.3% of all neoplasms. Most paragangliomas are defined as benign in nature, but 10-20% possess metastatic potential. There have been scattered reports of metastatic paraganglioma in the literature, but in rare circumstances, paragangliomas can metastasize to the spinal column causing destruction or compression of the spinal cord, clinically manifesting as pain or neurological deficit. We report a case of metastatic paraganglioma in which a 47-year-old man had spinal metastasis from a primary abdominal paraganglioma and was found to be positive for SDHB mutation, portraying negative implications for prognosis. Long-term follow-up is reported. In addition, we review the literature on the topic of metastatic paraganglioma, management of paragangliomas involving spine, and touch on the importance of the presence of SDHB mutations in these cases.
Darryl Lau; Frank La Marca; Sandra Camelo-Piragua; Paul Park
Related Documents :
17135789 - Recurrent arteriovenous malformation of the scrotum secondary to pelvic trauma.
747199 - Anterior-chamber damage as a result of mild ocular trauma.
24377829 - Giant invasive spinal schwannoma in children: a case report and review of the literature.
22964289 - Etiologic and epidemiologic analysis of hand, foot, and mouth disease in guangzhou city...
12780639 - Traumatic 'degloving' of the colon in blunt abdominal injury.
24627759 - Sirenomelia in a cameroonian woman: a case report and review of the literature.
5336559 - Pulmonary alveolar proteinosis. review of the literature with follow-up studies and rep...
7281509 - Renal malakoplakia. report of a case with giant michaelis-gutmann bodies.
2128699 - Counter immuno electrophoresis for the early diagnosis of acute pyogenic meningitis.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-8
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  -     ISSN:  1872-6968     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier B.V. All rights reserved.
Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The effect of Psoroptes ovis infestation on ovine epidermal barrier function.
Next Document:  Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes...