Document Detail

Metastatic low-grade endometrial stromal sarcoma of clitoris: report of a case.
MedLine Citation:
PMID:  17291270     Owner:  NLM     Status:  MEDLINE    
Low-grade endometrial stromal sarcoma (ESS) is an uncommon neoplasm, which has a highly recurrent nature. A review of the literature revealed that only one case of low-grade ESS, arising within the vulva from a focus of endometriosis, has been previously published. We describe an additional case of low-grade ESS arising within the vulva and to the best of our knowledge the first report of low-grade ESS metastasized to clitoris. A 46-year-old woman was admitted to our hospital due to a heavy uterine bleeding. A physical examination revealed a lesion in clitoris, which exhibited a densely cellular mesenchymal neoplasm on microscopy. On the basis of the pathologic features alone, a differential diagnosis of a low-grade ESS and cellular leiomyoma was considered. Seven months later, the patient presented again with excessive uterine bleeding and a total hysterectomy was performed. A tumor of white-tan, whorled appearance was found. Its features were suggestive of low-grade ESS. Taking into account the possible extrauterine location of an ESS and reviewing the first case, a diagnosis of rare low-grade ESS metastasized to clitoris was made.
A Androulaki; T G Papathomas; P Alexandrou; A C Lazaris
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society     Volume:  17     ISSN:  1048-891X     ISO Abbreviation:  Int. J. Gynecol. Cancer     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2007-02-12     Completed Date:  2007-03-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111626     Medline TA:  Int J Gynecol Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  290-3     Citation Subset:  IM    
Department of Pathology, Laiko General Hospital of Athens, Athens, Greece.
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MeSH Terms
Clitoris / pathology*
Endometrial Neoplasms / pathology*
Middle Aged
Sarcoma, Endometrial Stromal / pathology,  secondary*
Vulvar Neoplasms / secondary*

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