| Metastatic choroidal melanoma. | |
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MedLine Citation:
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PMID: 677236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied the metastatic pattern of 41 patients initially referred with a primary choroidal melanoma who later developed widespread disease. In the order of frequency, the most common sites of metastatic involvement were the liver (56%), subcutaneous tissue (36.5%), and bone (7%). Whereas the median interval between enucleation and the onset of metastatic disease was approximately four years, in rare cases, metastases were diagnosed concurrently with a primary choroidal melanoma. Since patients with choroidal melanomas usually survive less than one year after the development of widespread disease, a metastatic examination should be done in all patients with pigmented choroidal tumors both before and after ocular therapy. From the data obtained in this and other studies on metastatic melanoma, a reasonable basic metastatic examination for choroidal melanoma patients should include a serum lactic dehydrogenase, a serum alkaline phosphatase, a routine chest X-ray, and a general physical examination. |
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Authors:
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D H Char |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of ophthalmology Volume: 86 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 1978 Jul |
Date Detail:
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Created Date: 1978-09-25 Completed Date: 1978-09-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 76-80 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Bone Neoplasms / diagnosis Choroid Neoplasms / diagnosis*, mortality, pathology Female Humans Liver Neoplasms / diagnosis Male Melanoma / diagnosis*, mortality, pathology Middle Aged Neoplasm Metastasis / diagnosis*, mortality Soft Tissue Neoplasms / diagnosis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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