| Metastatic cerebral choriocarcinoma coexistent with a viable pregnancy. | |
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MedLine Citation:
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PMID: 8626104 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gestational choriocarcinoma associated with a viable pregnancy is extremely rare, and such choriocarcinoma with metastases presenting during the pregnancy is even more exceptional. Metastases from this tumor may present in a variety of ways depending on the site of the metastatic lesion, and can be fatal before choriocarcinoma is even suspected. We describe a 32-year-old primigravida presenting at 31 weeks gestation with a grand mal seizure due to cerebral metastases secondary to gestational choriocarcinoma who was subsequently successfully treated with chemotherapy. To our knowledge this is the first reported case of choriocarcinoma presenting with signs due to cerebral metastases during pregnancy where both the mother and child survived. This paper emphasizes the need to consider metastatic choriocarcinoma in any gravid female who presents with unusual neurological signs because of the life-threatening nature of this potentially curable disease. |
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Authors:
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A Dana; G J Saldanha; R Doshi; G J Rustin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Gynecologic oncology Volume: 61 ISSN: 0090-8258 ISO Abbreviation: Gynecol. Oncol. Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1996-06-21 Completed Date: 1996-06-21 Revised Date: 2006-04-24 |
Medline Journal Info:
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Nlm Unique ID: 0365304 Medline TA: Gynecol Oncol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 147-9 Citation Subset: IM |
Affiliation:
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Department of Medical Oncology, Charing Cross Hospital, London, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antineoplastic Combined Chemotherapy Protocols / therapeutic use Brain Neoplasms / diagnosis, drug therapy, secondary* Choriocarcinoma / diagnosis, drug therapy, secondary* Cyclophosphamide / administration & dosage Dactinomycin / administration & dosage Diagnosis, Differential Etoposide / administration & dosage Female Humans Methotrexate / administration & dosage Pregnancy Pregnancy Complications, Neoplastic* Vincristine / administration & dosage |
| Chemical | |
Reg. No./Substance:
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0/EMA-CO protocol; 33419-42-0/Etoposide; 50-18-0/Cyclophosphamide; 50-76-0/Dactinomycin; 57-22-7/Vincristine; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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