Document Detail


Metastatic carcinoma in the neck: a clinical, radiological, scintigraphic and pathological study.
MedLine Citation:
PMID:  1649018     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was undertaken to compare clinical evaluation of the neck with 99mTc(v) DMSA planar scintigraphy and computerized tomography (CT) in patients with head and neck carcinoma. Twenty-six patients were studied and in all but one the neck was previously untreated. A total of 31 neck dissections were performed and the specimens examined histopathologically. CT was approximately as accurate (71%) as clinical examination (68%) and more accurate than 99mTc(v) DMSA planar scintigraphy (48%) in predicting which necks contained metastatic carcinoma. Overall, 13% of necks had their staging correctly changed by 99mTc(v) DMSA scintigraphy compared with 10% for CT. Although scintigraphy upstaged 13% of clinically N0 necks compared to 6% for CT, it was less sensitive and specific than either clinical examination or CT. 99mTc(v) DMSA planar scintigraphy has no role to play in the investigation of patients with metastatic carcinoma to include the clinically N0 neck.
Authors:
J C Watkinson; C E Todd; L Paskin; S Rankin; T Palmer; O H Shaheen; S E Clarke
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Clinical otolaryngology and allied sciences     Volume:  16     ISSN:  0307-7772     ISO Abbreviation:  Clin Otolaryngol Allied Sci     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-08-21     Completed Date:  1991-08-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7701793     Medline TA:  Clin Otolaryngol Allied Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  187-92     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Guy's Hospital, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / secondary
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell / pathology,  radiography,  radionuclide imaging,  secondary*
Female
Head and Neck Neoplasms / pathology,  radiography,  radionuclide imaging,  secondary*
Humans
Lymph Node Excision
Male
Middle Aged
Neoplasm Staging
Organotechnetium Compounds / diagnostic use
Palpation
Succimer / diagnostic use
Technetium Tc 99m Dimercaptosuccinic Acid
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Organotechnetium Compounds; 304-55-2/Succimer; 65438-08-6/Technetium Tc 99m Dimercaptosuccinic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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