| Metastatic carcinoid disease inducing coronary vasospasm. | |
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MedLine Citation:
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PMID: 22412234 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Herein, we report a case of progressive coronary vasospasm in a 70-year-old man who had a long-standing history of metastatic gastrointestinal carcinoid tumor. Despite octreotide, nitrate, and calcium channel-blocker therapy, the patient's urinary 5-hydroxy-indole acetic acid level increased, coinciding with an increased frequency of flushing episodes with chest discomfort. In the cardiac catheterization laboratory, we captured an episode that was associated with diffuse right coronary artery spasm, ST-segment elevation, and intense symptoms. We attribute the patient's coronary vasospasm to his metastatic carcinoid disease. |
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Authors:
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Danny J Eapen; Stephen Clements; Peter Block; Laurence Sperling |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital Volume: 39 ISSN: 1526-6702 ISO Abbreviation: Tex Heart Inst J Publication Date: 2012 |
Date Detail:
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Created Date: 2012-03-13 Completed Date: 2012-11-12 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 8214622 Medline TA: Tex Heart Inst J Country: United States |
Other Details:
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Languages: eng Pagination: 76-8 Citation Subset: IM |
Affiliation:
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Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA. deapen@emory.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Alcohol Drinking / adverse effects Antineoplastic Agents, Hormonal / therapeutic use Biological Markers / urine Carcinoid Heart Disease / diagnosis, etiology*, therapy Carcinoid Tumor / complications*, drug therapy, secondary Cardiac Catheterization Coronary Angiography Coronary Vasospasm / diagnosis, etiology*, therapy Electrocardiography Gastrointestinal Neoplasms / complications*, drug therapy, pathology Humans Hydroxyindoleacetic Acid / urine Male Octreotide / therapeutic use Stents Treatment Outcome Vasodilator Agents / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents, Hormonal; 0/Biological Markers; 0/Vasodilator Agents; 54-16-0/Hydroxyindoleacetic Acid; 83150-76-9/Octreotide |
| Comments/Corrections | |
Comment In:
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Tex Heart Inst J. 2012;39(3):460
[PMID:
22719174
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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