Document Detail

Metastatic bilateral malignant ovarian tumors associated with pregnancy.
MedLine Citation:
PMID:  19574181     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Krukenberg tumors in pregnancy are extremely rare. Only three cases have been reported, two of which were diagnosed postpartum.
CASE REPORT: A 20-year-old, primigravida with bilateral malignant ovarian tumors, who received no prior antenatal care, was presented with intestinal obstruction at 5 months' gestation. Pregnancy was preserved, and bilateral oophorectomy, omentectomy with resection of sigmoid colon growth, and colostomy were performed. The patient aborted spontaneously and postoperatively, and was treated with adjuvant chemotherapy.
CONCLUSION: Because platinum-based chemotherapy can be safely given during pregnancy, hysterectomy can be avoided in cases of bilateral malignant ovarian tumors if the uterus is not grossly involved, so allowing preservation of an existing pregnancy.
Savita Rani Singhal; Smiti Nanda; Pooja Chaudhry; Jyotsna Sen; Suresh Kumar Singhal
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Taiwanese journal of obstetrics & gynecology     Volume:  48     ISSN:  1875-6263     ISO Abbreviation:  Taiwan J Obstet Gynecol     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-07-03     Completed Date:  2009-10-21     Revised Date:  2011-12-02    
Medline Journal Info:
Nlm Unique ID:  101213819     Medline TA:  Taiwan J Obstet Gynecol     Country:  China    
Other Details:
Languages:  eng     Pagination:  167-8     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Pandit Bhagwat Dayal Sharma Postgraduate Institute, Medical Sciences, Rohtak, Haryana, India.
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MeSH Terms
Abortion, Spontaneous
Adenocarcinoma, Mucinous / drug therapy*,  secondary*,  surgery
Antibiotics, Antineoplastic / therapeutic use
Antineoplastic Agents, Alkylating / therapeutic use
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Cisplatin / therapeutic use
Colonic Neoplasms / pathology*
Combined Modality Therapy
Cyclophosphamide / therapeutic use
Doxorubicin / therapeutic use
Omentum / surgery
Ovarian Neoplasms / drug therapy,  secondary*,  surgery
Pregnancy Complications, Neoplastic / ultrasonography*
Young Adult
Reg. No./Substance:
0/Antibiotics, Antineoplastic; 0/Antineoplastic Agents, Alkylating; 15663-27-1/Cisplatin; 23214-92-8/Doxorubicin; 50-18-0/Cyclophosphamide
Comment In:
Taiwan J Obstet Gynecol. 2011 Sep;50(3):405-6; author reply 407   [PMID:  22030067 ]

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