Document Detail

Metastatic basal cell carcinoma of the posterior neck: case report and review of the literature.
MedLine Citation:
PMID:  22515224     Owner:  NLM     Status:  Publisher    
Although primary basal cell carcinoma (BCC) represents an extremely common malignancy, metastases derived from BCC are exceedingly rare. The prognosis for metastatic BCC is poor, and little consensus exists regarding predictive factors or optimal treatment strategies. Here, we present the case of a 63-year-old man with BCC of the neck who subsequently developed multiple metastases to subcutaneous tissue, lymph nodes, and the parotid gland. Risk factors and clinical features of metastatic BCC are reviewed, as is the relationship of histopathologic subtype to metastatic behavior. Current chemotherapeutic and targeted therapies also are discussed in the context of recent advances in molecular biology. Gropper AB, Girouard SD, Hojman LP, Huang SJ, Qian X, Murphy GF, Vleugels RA. Metastatic basal cell carcinoma of the posterior neck: case report and review of the literature.
Adrienne B Gropper; Sasha D Girouard; Lia P Hojman; Susan J Huang; Xiaohua Qian; George F Murphy; Ruth Ann Vleugels
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Publication Detail:
Journal Detail:
Title:  Journal of cutaneous pathology     Volume:  39     ISSN:  1600-0560     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-4-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425124     Medline TA:  J Cutan Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  526-534     Citation Subset:  -    
Copyright Information:
Copyright © 2012 John Wiley & Sons A/S.
Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA Program in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA Department of Dermatology, Hospital Clinico, Universidad de Chile, Santiago, Chile Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
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