| Metastatic amelanotic nodular melanoma during pregnancy. | |
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MedLine Citation:
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PMID: 18660642 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This case report presents a very aggressive course of amelanotic nodular melanoma during pregnancy resulting in death five months after delivery. A 34 year-old Caucasian woman at 19th week of the second pregnancy was diagnosed having amelanotic nodular melanoma (tumor thickness - 2.5 mm) with metastases to the regional right inguinal lymph node. Amelanotic nodular melanoma represents malignant melanocytic tumor of the skin, which clinically mimics a variety of benign and malignant skin conditions and therefore commonly leads to delayed diagnosis. Though primary tumor was excised immediately, other treatment procedures as radical lymphadenectomy and chemotherapy were delayed, and immunotherapy was not given totally. At the 29th week of pregnancy, the woman via naturalem delivered a healthy female child, and the chemotherapy was started. Since pregnancy limits the prescription of immunotherapy and chemotherapy, the prognosis for melanoma during pregnancy detected later than in the second stage is poor and can be illustrated by our reported case. Such patients seems to be at higher risk to develop metastasis of melanoma in the internal organs and occasionally even in the fetus; therefore, they should be timely informed about that. |
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Authors:
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Daiva Jasaitiene; Skaidra Valiukeviciene; Jurgita Makstiene; Edita Brone Juodzbaliene |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Medicina (Kaunas, Lithuania) Volume: 44 ISSN: 1648-9144 ISO Abbreviation: Medicina (Kaunas) Publication Date: 2008 |
Date Detail:
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Created Date: 2008-07-28 Completed Date: 2008-10-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9425208 Medline TA: Medicina (Kaunas) Country: Lithuania |
Other Details:
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Languages: eng Pagination: 467-71 Citation Subset: IM |
Affiliation:
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Department of Skin and Venereal Diseases, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania. daiva@dr.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Immunohistochemistry Infant, Newborn Lymph Node Excision Lymphatic Metastasis Melanoma, Amelanotic / diagnosis, mortality, pathology, secondary*, surgery Pregnancy Pregnancy Complications, Neoplastic* / diagnosis, mortality, pathology, surgery Pregnancy Trimester, Second Pregnancy Trimester, Third Prognosis Puerperal Disorders / mortality Skin / pathology Skin Neoplasms / diagnosis, mortality, pathology, secondary*, surgery Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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