| Metastatic pancreatic adenocarcinoma: current standards, future directions. | |
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MedLine Citation:
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PMID: 19636248 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pancreatic cancer is the fourth most common cause of cancer death in the United States. In the landmark study in 1997, which established the central although modest role of gemcitabine in this disease, progress has been incremental. Significant developments have been an increased acceptance for combination chemotherapy in patients with good performance status in addition to an increased understanding of tumorigenesis. The parallel technologic and engineering developments that have occurred hold the promise of exploiting this understanding. This review attempts to summarize the standard therapeutic approach to metastatic pancreatic cancer and point to areas that hold promise for the future. |
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Authors:
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Austin Duffy; Shivaani Kummar |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Intramural; Review |
Journal Detail:
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Title: American journal of therapeutics Volume: 17 ISSN: 1536-3686 ISO Abbreviation: Am J Ther Publication Date: 2010 Jan-Feb |
Date Detail:
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Created Date: 2010-01-22 Completed Date: 2010-03-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9441347 Medline TA: Am J Ther Country: United States |
Other Details:
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Languages: eng Pagination: 79-85 Citation Subset: IM |
Affiliation:
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Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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drug therapy*,
pathology Antineoplastic Combined Chemotherapy Protocols / therapeutic use* Clinical Trials as Topic Deoxycytidine / administration & dosage, analogs & derivatives Humans Neoplasm Metastasis Pancreatic Neoplasms / drug therapy*, pathology |
| Chemical | |
Reg. No./Substance:
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103882-84-4/gemcitabine; 951-77-9/Deoxycytidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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