| Metastatic extra-adrenal sympathetic paraganglioma in a horse. | |
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MedLine Citation:
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PMID: 20153870 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Post-mortem examination was performed on a horse that died after exhibiting signs of colic. Gross findings included haemoperitoneum and a large round encapsulated mass located in the sublumbar area cranial to the left kidney. On sectioning the mass was solid red to brown and small nodules of similar tissue were noted at the periphery of the mass. The spleen was firm and three nodules were found in one thyroid gland. Microscopically, the abdominal mass, adjacent nodules, the spleen and one thyroid nodule consisted of clusters and cords of round to oval neoplastic cells, separated by a fine collagen and reticulin fibre network. Immunohistochemically, tumour cells expressed chromogranin A, synaptophysin and neuron-specific enolase, but did not express cytokeratin. The findings were consistent with a metastatic extra-adrenal sympathetic paraganglioma. |
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Authors:
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N Herbach; W Breuer; W Hermanns |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-02-13 |
Journal Detail:
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Title: Journal of comparative pathology Volume: 143 ISSN: 1532-3129 ISO Abbreviation: J. Comp. Pathol. Publication Date: 2010 Aug-Oct |
Date Detail:
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Created Date: 2010-07-20 Completed Date: 2010-12-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0102444 Medline TA: J Comp Pathol Country: England |
Other Details:
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Languages: eng Pagination: 199-202 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Institute of Veterinary Pathology, Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Munich, Germany. n.herbach@lmu.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Autonomic Nervous System Diseases / pathology, veterinary* Chromogranin A / metabolism Fatal Outcome Horse Diseases / metabolism, pathology* Horses Immunohistochemistry Male Nuclear Proteins / metabolism Paraganglioma, Extra-Adrenal / metabolism, secondary, veterinary* Peritoneal Neoplasms / metabolism, secondary, veterinary* Synaptophysin / metabolism Thyroid Gland / pathology Thyroid Neoplasms / metabolism, pathology, veterinary* |
| Chemical | |
Reg. No./Substance:
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0/Chromogranin A; 0/Nuclear Proteins; 0/Synaptophysin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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