Document Detail


Metastasis suppressor genes.
MedLine Citation:
PMID:  23348381     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Metastasis is a major cause of cancer mortality. Metastasis is a complex process that requires the regulation of both metastasis-promoting and metastasis suppressor genes. The discovery of metastasis suppressor genes contributes significantly to our understanding of metastasis mechanisms and provides prognostic markers and therapeutic targets in clinical cancer management. In this review, we summarize the methods that have been used to identify metastasis suppressors and the potential clinical impact of these genes.
Authors:
Jinchun Yan; Qin Yang; Qihong Huang
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Histology and histopathology     Volume:  28     ISSN:  1699-5848     ISO Abbreviation:  Histol. Histopathol.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-01-25     Completed Date:  2013-07-11     Revised Date:  2014-02-05    
Medline Journal Info:
Nlm Unique ID:  8609357     Medline TA:  Histol Histopathol     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  285-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Gene Expression Regulation, Neoplastic*
Gene Silencing
Genes, Tumor Suppressor*
Genomics
Humans
Neoplasm Metastasis
Neoplasms / diagnosis,  genetics*
Prognosis
Grant Support
ID/Acronym/Agency:
R01 CA148759/CA/NCI NIH HHS; R01CA148759/CA/NCI NIH HHS
Comments/Corrections

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