| Metastases to the Spleen in 59 cancer patients: a 14-year clinicosonographic study | |
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MedLine Citation:
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PMID: 17492575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To describe B-mode sonographic patterns of splenic metastases and to evaluate clinical data regarding tumour staging, kind of tumour and survival of patients with splenic metastases. METHODS: From 1988 till October 2002, about 168 000 abdominal examinations were performed in an internal ultrasound laboratory. During this time, n = 59 patients with splenic metastases were detected who qualified for the retrospective study design. The following data were evaluated: echomorphology of splenic metastases, tumour staging, kind of underlying tumour, and survival rates of patients with splenic metastases. RESULTS: The median age of patients was 61.8 years (SD +/- 10.9). Lesions were hypoechoic n = 19 (32%), isoechoic n = 15 (25.5%), hyperechoic n = 10 (17%) und complex n = 15 (25.5%). A hypoechoic rim was found in n = 18 patients (31 %). An additional spread into other organs was seen in 56 cases (95%). Underlying cancers were carcinoma of unknown primary tumours (CUP) n = 12 (20.3%), lung cancer n = 11 (18.6 %), ovarian cancer n = 7 (11.9%), colorectal cancer n = 6 (10.2%), breast cancer n = 6 (10.2%), malignant melanoma n = 5 (8.4 %), and others n = 12 (20.3%). The median survival time for all patients was 8.7 months. The worst prognosis within the subgroup analysis was found for patients with CUP-syndrome who had a median survival time of 2.7 months. CONCLUSION: The sonographic pattern of splenic metastases is variable. Metastases to the spleen indicate a terminal stage cancer disease and is associated with an extremely short survival time. 20 % of underlying cancers were CUP-syndromes with the worst prognosis of all subgroups. |
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Authors:
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C Görg; A Hoffmann |
Publication Detail:
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Type: English Abstract; Journal Article Date: 2007-05-09 |
Journal Detail:
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Title: Ultraschall in der Medizin (Stuttgart, Germany : 1980) Volume: 29 ISSN: 0172-4614 ISO Abbreviation: Ultraschall Med Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-04-18 Completed Date: 2008-08-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8303585 Medline TA: Ultraschall Med Country: Germany |
Other Details:
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Languages: ger Pagination: 173-8 Citation Subset: IM |
Affiliation:
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Hämatologie, Universität Giessen und Marburg, Standort Marburg. goergc@med.uni-marburg.de |
Vernacular Title:
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Milzmetastasen bei 59 Patienten mit Karzinomen: Eine klinisch sonografische Studie über einen Zeitraum von 14 Jahren. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Breast Neoplasms / pathology Colorectal Neoplasms / pathology Female Humans Lung Neoplasms / pathology Melanoma / pathology Middle Aged Neoplasm Metastasis / ultrasonography* Neoplasms, Unknown Primary / pathology Retrospective Studies Splenic Neoplasms / mortality, secondary*, ultrasonography* Survival Analysis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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