| Metastases and the normalization of tumour blood vessels by ICRF 159: a new type of drug action. | |
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MedLine Citation:
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PMID: 18663794 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Profound modification of the structure and arrangement of the blood vessels has been shown in tumours after treatment with ICRF 159. X-ray angiography, carbon black (Pelikan ink) labelling, and intravital staining with lissamine green were used to demonstrate the changes. Alteration of the morphology of the blood vessels at the edge of a tumour may affect the escape of malignant cells and the rate of blood flow (and thus the concentration of anticancer drugs) through the tumour. |
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Authors:
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A W Le Serve; K Hellmann |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical & experimental metastasis Volume: 25 ISSN: 0262-0898 ISO Abbreviation: Clin. Exp. Metastasis Publication Date: 2008 |
Date Detail:
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Created Date: 2008-07-28 Completed Date: 2008-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8409970 Medline TA: Clin Exp Metastasis Country: Netherlands |
Other Details:
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Languages: eng Pagination: 283-8 Citation Subset: - |
Affiliation:
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Department of Cancer Chemotherapy, Imperial Cancer Research Fund, London, UK. |
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Republished from:
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Br Med J. 1972 Mar 4;1(5800):597-601
[PMID:
4111169
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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