Document Detail


Metal-catalyzed rearrangements of 3-allenyl 3-hydroxyindolin-2-ones in the presence of halogenated reagents.
MedLine Citation:
PMID:  23314199     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The reactions of 3-allenyl 3-hydroxyoxindoles with a variety of halogenated reagents in the presence of catalytic amounts of precious metal salts were explored. Both, rearrangement and oxycyclization reactions to give 4-(1-halovinyl)-quinolinediones or spirocyclic halooxindoles, respectively, are competitive pathways. The kind of functionalization is substrate and reaction conditions dependent.
Authors:
Benito Alcaide; Pedro Almendros; Amparo Luna; Natividad Prieto
Related Documents :
23477289 - Asymmetric synthesis of l-carbidopa based on a highly enantioselective α-amination.
2903929 - Antihypertensive activity in a series of 1-piperazino-3-phenylindans with potent 5-ht2-...
23718209 - Mechanistic and preparative studies of radical chain homolytic substitution reactions o...
19726199 - Rational design and synthesis of highly potent anti-acetylcholinesterase activity huper...
23473099 - Effective synthesis of 3'-deoxy-3'-azido nucleosides for antiviral and antisense ribonu...
25006789 - Glutaraldehyde cross-linking of immobilized thermophilic esterase on hydrophobic macrop...
24915449 - A free radical cascade cyclization of isocyanides with simple alkanes and alcohols.
22724899 - Activation of h(2)o(2) by chiral confined brønsted acids: a highly enantioselective ca...
14627399 - Regioselective allylmetalation of allenes with tetraallylmanganate or allylmagnesium ch...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-14
Journal Detail:
Title:  Organic & biomolecular chemistry     Volume:  -     ISSN:  1477-0539     ISO Abbreviation:  Org. Biomol. Chem.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101154995     Medline TA:  Org Biomol Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Grupo de Lactamas y Heterociclos Bioactivos, Departamento de Química Orgánica I, Unidad Asociada al CSIC, Facultad de Química, Universidad Complutense de Madrid, 28040-Madrid, Spain. alcaideb@quim.ucm.es.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Analysis of PIK3CA exon 9 and 20 mutations in breast cancers using PCR-HRM and PCR-ARMS: Correlation...
Next Document:  Urinary environmental chemical concentrations and vitamin D are associated with vision, hearing, and...