Document Detail

Metachronous thromboses and myocardial infarctions in a 32-year-old woman with antiphospholipid antibodies.
MedLine Citation:
PMID:  11805747     Owner:  NLM     Status:  MEDLINE    
Metachronous thromboses in multiple vascular beds in a patient younger than 40 years is often suggestive of an acquired or congenital thrombophilic disorder. We present the case of a 32-year-old African American woman who presented to the emergency room with a painful right neck mass and a right hemispheric transient ischemic attack. She had 2 prior admissions for recurrent myocardial infarctions, hypertensive crises, congestive heart failure, and a left ventricular thrombus. Her warfarin therapy expired 2 weeks before her current admission. Our expanded evaluation for thrombophilia revealed high antiphospholipid antibody levels. High-dose anticoagulants were administered without further recurrence or complications. The antiphospholipid antibody syndrome should be considered early in the differential diagnosis as an important cause of recurrent, unusual, or unexplained thromboses in young patients. Education and patient compliance are vital to successful long-term medical management.
Irwin M Best; Geetanjali Vasandani; Harvey L Bumpers; George Rust
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Heart & lung : the journal of critical care     Volume:  31     ISSN:  0147-9563     ISO Abbreviation:  Heart Lung     Publication Date:    2002 Jan-Feb
Date Detail:
Created Date:  2002-01-23     Completed Date:  2002-03-13     Revised Date:  2006-08-28    
Medline Journal Info:
Nlm Unique ID:  0330057     Medline TA:  Heart Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  30-3     Citation Subset:  AIM; IM    
Morehouse School of Medicine, Department of Surgery, Atlanta, GA 30310-1495, USA.
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MeSH Terms
Anticoagulants / therapeutic use*
Antiphospholipid Syndrome / complications*,  diagnosis*,  drug therapy
Diagnosis, Differential
Myocardial Infarction / etiology*
Neck Pain / etiology
Patient Compliance
Thrombosis / etiology*
Treatment Outcome
Warfarin / therapeutic use*
Reg. No./Substance:
0/Anticoagulants; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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