| Metabolism and effects of organic compounds in animals. | |
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MedLine Citation:
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PMID: 2997977 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In recent years, society has become increasingly aware and concerned about protection from chemicals released into the environment. The knowledge of the metabolism and effects of organic compounds in animals, specifically food-producing animals, are of paramount importance in assessing potential human health hazards. An intensive effort has been directed at detection of chemicals in the environment, determination of their physiological insult and cellular interaction; in particular their carcinogenic and mutagenic induction capability. The chemical exposure of food-producing animals can be extremely difficult to evaluate and quite devastating. The exposure of food-producing animals to polybrominated biphenyls (PBBs) and polychlorinated biphenyls (PCBs) emphasizes the seriousness of the problem. The polycyclic aromatic hydrocarbons (PAHs), capable of inducing cancer in experimental animals, have been studied extensively in laboratory animals. Current studies deal with the mechanism of metabolism of PAHs and the ultimate carcinogenic form. Although our knowledge concerning the health hazards of organic chemicals is continually increasing, its impact on food-producing animals and man's food chain is poorly understood. Awareness of the problem by practicing veterinarians and toxicologists, environmental toxicologists and public health officials is required to evaluate the impact of organic chemicals on the human food chain. |
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Authors:
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G R Eisele |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
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Title: Veterinary and human toxicology Volume: 27 ISSN: 0145-6296 ISO Abbreviation: Vet Hum Toxicol Publication Date: 1985 Oct |
Date Detail:
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Created Date: 1985-12-16 Completed Date: 1985-12-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7704194 Medline TA: Vet Hum Toxicol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 417-21 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Domestic / metabolism* Environmental Pollutants / metabolism*, toxicity Food Contamination Polybrominated Biphenyls / metabolism, toxicity Polychlorinated Biphenyls / metabolism, toxicity Polycyclic Compounds / metabolism, toxicity |
| Chemical | |
Reg. No./Substance:
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0/Environmental Pollutants; 0/Polybrominated Biphenyls; 0/Polychlorinated Biphenyls; 0/Polycyclic Compounds |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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