Document Detail


Metabolism, cell growth and the bacterial cell cycle.
MedLine Citation:
PMID:  19806155     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Adaptation to fluctuations in nutrient availability is a fact of life for single-celled organisms in the 'wild'. A decade ago our understanding of how bacteria adjust cell cycle parameters to accommodate changes in nutrient availability stemmed almost entirely from elegant physiological studies completed in the 1960s. In this Opinion article we summarize recent groundbreaking work in this area and discuss potential mechanisms by which nutrient availability and metabolic status are coordinated with cell growth, chromosome replication and cell division.
Authors:
Jue D Wang; Petra A Levin
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2009-10-06
Journal Detail:
Title:  Nature reviews. Microbiology     Volume:  7     ISSN:  1740-1534     ISO Abbreviation:  Nat. Rev. Microbiol.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-16     Completed Date:  2009-11-23     Revised Date:  2012-02-14    
Medline Journal Info:
Nlm Unique ID:  101190261     Medline TA:  Nat Rev Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  822-7     Citation Subset:  IM    
Affiliation:
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA. jdwang@bcm.edu
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MeSH Terms
Descriptor/Qualifier:
Bacillus subtilis / cytology,  growth & development,  metabolism
Cell Cycle*
Cell Cycle Proteins
Cell Division
Culture Media*
DNA Replication
Escherichia coli* / cytology,  growth & development,  metabolism
Gene Expression Regulation, Bacterial
Grant Support
ID/Acronym/Agency:
DP2 OD 004433/OD/NIH HHS; DP2 OD004433-01/OD/NIH HHS; GM084003/GM/NIGMS NIH HHS; GM64671/GM/NIGMS NIH HHS; R01 GM064671-07/GM/NIGMS NIH HHS; R01 GM084003-01A1/GM/NIGMS NIH HHS; R01 GM084003-03/GM/NIGMS NIH HHS; R01 GM084003-04/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Cell Cycle Proteins; 0/Culture Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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