Document Detail


Metabolic syndrome in antipsychotic naïve patients diagnosed with schizophrenia.
MedLine Citation:
PMID:  22176701     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aim: The article aims to study the prevalence of metabolic syndrome (MS) and subthreshold MS in antipsychotic naïve patients with schizophrenia. Materials and methods: Forty-six antipsychotic naïve patients diagnosed with schizophrenia were evaluated for the presence of metabolic abnormalities using International Diabetes Federation and modified National Cholesterol Education Program - Third Adult Treatment Panel criteria. Results: Five patients (10.86%) fulfilled International Diabetes Federation criteria for MS and six patients (13.04%) met modified National Cholesterol Education Program - Third Adult Treatment Panel criteria for MS. Additionally, 14 (30.43%) more patients fulfilled 2 out of the 5 criteria for MS and another 19 (41.3%) fulfilled 1 criterion for MS. Of the 19 patients who fulfilled one criterion for MS, 18 had an abnormality other than increase in waist circumference. Conclusion: Findings of the present study suggest that although only few antipsychotic naïve patients diagnosed with schizophrenia have MS, a significantly large proportion of patients have subsyndromal MS. Awareness of this in clinicians can have implications in the selection of antipsychotic medication.
Authors:
Sandeep Grover; Naresh Nebhinani; Subho Chakrabarti; Preeti Parakh; Deepak Ghormode
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-18
Journal Detail:
Title:  Early intervention in psychiatry     Volume:  -     ISSN:  1751-7893     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101320027     Medline TA:  Early Interv Psychiatry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Blackwell Publishing Asia Pty Ltd.
Affiliation:
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
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