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Metabolic syndrome and chronic kidney disease in a rural Chinese population.
MedLine Citation:
PMID:  21801716     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Metabolic syndrome is a common risk factor for cardiovascular disease. Chronic kidney disease (CKD) is a worldwide public health problem. We investigated the association between metabolic syndrome and CKD in a rural Chinese population. METHODS: This was a cross-sectional study using data from the Handan Eye Study. RESULTS: 4944 of participants aged ≥30y were included in this analysis. Participants with metabolic syndrome had a higher prevalence of CKD (20.9% vs.15.8%, P<0.001) than those without. As the number of metabolic syndrome components increased, so did the prevalence of CKD (P<0.001). The multivariate-adjusted odds ratio (OR) of chronic kidney disease in participants with the metabolic syndrome was 1.293 (95% CI 1.093-1.529) compared with those without. In multivariate logistic regression analysis, high blood pressure (OR 1.348; 95% CI 1.122-1.619) and high fasting glucose (OR 1.501; 95% CI 1.235-1.794) were independently associated with the risk for CKD. Compared with participants without any component, multivariate adjusted OR for CKD was 1.316 (95%CI 1.004-1.723), 1.397(95%CI 1.038-1.882), 1.672 (95%CI 1.183-2.363) for those with 2, 3, 4 or 5 components, respectively. CONCLUSION: In this rural Chinese population aged ≥30y, metabolic syndrome was associated with CKD.
Authors:
Liping Jiang; Yuanbo Liang; Bo Qiu; Fenghua Wang; Xinrong Duan; Xiaohui Yang; Jingang Yang; Wen Huang; Ningli Wang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-23
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  -     ISSN:  1873-3492     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-8-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier B.V. All rights reserved.
Affiliation:
Department of Nephrology, Beijing TongRen Hospital, Capital Medical University, Beijing, China.
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