Document Detail

Metabolic substrates, muscle fibre composition and fibre size in late walking and normal children.
MedLine Citation:
PMID:  421694     Owner:  NLM     Status:  MEDLINE    
In 10 children with delayed walking, muscle specimens were obtained by needle biopsy from the vastus lateralis muscle for determination of ATP, creatine phosphate (CP), glycogen and lactate concentration, as well as fibre composition and fibre size. The values obtained are compared with corresponding results for a control group of 25 children aged 2 months--11 years. Details of the control series are given and its validity as a reference group is discussed. Six children (group I) who showed minor gross motor delay but otherwise normal development at follow-up were found to have lowered ATP, CP and glycogen concentrations, compared to 4 children (group II) who had general developmental delay, and to the control group. The children in group I were shown to have smaller fibre size and a greater difference between type 1 and 2 fibres than the children in group II and in the control group. No differences in the concentrations of metabolic substrates or the morphometric values could be detected between group II and the control group.
A Lundberg; B O Eriksson; G Mellgren
Related Documents :
24139164 - Melanocortin-4 receptor polymorphism rs17782313: association with obesity and eating in...
2308034 - Intellectual and functional status at school entry of children who weighed 1000 grams o...
1089974 - Oral-pharyngeal development and evaluation.
7591674 - Prospective study of gross motor development in children with sma type ii.
8995464 - Thyroid ultrasound findings 7 years after the chernobyl accident. a comparative epidemi...
6966684 - Effect of upper respiratory tract infection on eustachian tube ventilatory function in ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  130     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1979 Feb 
Date Detail:
Created Date:  1979-05-16     Completed Date:  1979-05-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  79-92     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenosine Triphosphate / analysis
Age Factors
Child, Preschool
Glycogen / analysis
Lactates / analysis
Motor Skills*
Muscles / analysis*
Phosphocreatine / analysis
Time Factors
Reg. No./Substance:
0/Lactates; 56-65-5/Adenosine Triphosphate; 67-07-2/Phosphocreatine; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Epidemiological and preventive aspects of cerebral palsy and severe mental retardation in Sweden.
Next Document:  Muscle abnormalities in coeliac disease: studies on gross motor development and muscle fibre composi...