Document Detail

Metabolic studies in rats under glucose and glycerol loading.
MedLine Citation:
PMID:  528159     Owner:  NLM     Status:  MEDLINE    
It has been found in rats that 40% glycerol, when added to standard diet, reduces the food intake and thus prevents weight gain. The subcutaneous application (40 mg/kg three times daily) has no effect. Under pair feeding conditions the oxygen consumption, the RQ value and body weight remain unaffected as compared with controls receiving glucose. It is concluded that reduction of body weight induced by glycerol feeding is due to reduced amount of food intake and not due to any alterations of energy metabolism.
P Om; M Hohenegger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition     Volume:  49     ISSN:  0300-9831     ISO Abbreviation:  Int J Vitam Nutr Res     Publication Date:  1979  
Date Detail:
Created Date:  1980-04-23     Completed Date:  1980-04-23     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  1273304     Medline TA:  Int J Vitam Nutr Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  317-21     Citation Subset:  IM    
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MeSH Terms
Blood Glucose / analysis
Body Weight / drug effects
Carbon Dioxide / physiology
Eating / drug effects
Energy Metabolism / drug effects*
Glucose / administration & dosage,  pharmacology*
Glycerol / administration & dosage,  blood,  pharmacology*
Injections, Subcutaneous
Oxygen / physiology
Oxygen Consumption / drug effects
Respiration / drug effects
Reg. No./Substance:
0/Blood Glucose; 124-38-9/Carbon Dioxide; 50-99-7/Glucose; 56-81-5/Glycerol; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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