Document Detail


Metabolic and structural impairment of skeletal muscle in heart failure.
MedLine Citation:
PMID:  23065040     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Physiologic endurance exercise performance is primarily limited by cardiac function. In patients with heart failure, there is dissociation between cardiac performance and exercise capacity, suggesting a distinct role of abnormal peripheral organ function, including skeletal muscle function. The impact of heart failure upon skeletal muscle and exercise performance will be discussed with a focus on molecular, structural, and functional derangements in skeletal muscle of patients with heart failure.
Authors:
Cynthia Zizola; P Christian Schulze
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Heart failure reviews     Volume:  18     ISSN:  1573-7322     ISO Abbreviation:  Heart Fail Rev     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-09-25     Completed Date:  2014-05-30     Revised Date:  2014-09-02    
Medline Journal Info:
Nlm Unique ID:  9612481     Medline TA:  Heart Fail Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  623-30     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Energy Metabolism*
Heart Failure / metabolism*,  pathology
Humans
Muscle, Skeletal / metabolism*,  pathology
Myocytes, Cardiac / metabolism*,  pathology*
Grant Support
ID/Acronym/Agency:
K23 HL095742/HL/NHLBI NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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