| Metabolic performance of free fed rats subjected to prolonged fast as compared to the metabolic pattern in rats under long term food restriction. | |
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MedLine Citation:
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PMID: 6395149 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Glycemia, free fatty acids, insulinemia, hepatic glycogen, adrenal ascorbic acid, the amount of food ingested and of feces eliminated, gastric emptying and body weight were measured in two groups of rats of the same age. The F, free fed group was subjected to fast during 22 hours and then had a final meal for two hours. The R rats, subjected to food restriction from one to four weeks, had also a final two hour meal after the regular period of 22 hours with no access to food, and then both groups were treated equally. Coincidently, gastric emptying was more delayed, liver glycogen concentration was highest and glycemia was better maintained in the R than the F rats, particularly after three and four weeks of training. Probably due to their greater dependence upon the more frequent supply of nutrients, the F group had a larger free fatty acids mobilization during fast. Adrenal hyperactivity was induced in both groups and the amount of food ingested progressively increased in the R group and decreased in the F group. In general the metabolic efficiency tended to converge to a similar order of magnitude in both groups of animals by the end of the third week. A delayed gastric emptying seems to be a major factor in the adaptations to food restriction. |
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Authors:
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R Curi; N S Hell; R B Bazotte; C Timo-Iaria |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Physiology & behavior Volume: 33 ISSN: 0031-9384 ISO Abbreviation: Physiol. Behav. Publication Date: 1984 Oct |
Date Detail:
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Created Date: 1985-03-18 Completed Date: 1985-03-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0151504 Medline TA: Physiol Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 525-31 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Glands
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analysis Animals Ascorbic Acid / analysis Blood Glucose / analysis Body Weight Defecation Fatty Acids, Nonesterified / blood Food Deprivation / physiology* Insulin / blood Liver Glycogen / analysis Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Fatty Acids, Nonesterified; 0/Liver Glycogen; 11061-68-0/Insulin; 50-81-7/Ascorbic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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