| Metabolic, nutritional, iatrogenic, and artifactual sources of urinary organic acids: a comprehensive table. | |
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MedLine Citation:
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PMID: 11978597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The determination of organic acids and glycine conjugates in urine is key for the diagnosis and follow-up of several inborn errors of metabolism (IEM). However, clinical interpretations may still be hindered by ambiguity in the sources of some urinary organic acids and acylglycines as well as in the relationship between their excretion and IEM. APPROACH: Relevant data have been compiled from major books and references on the topic and by exhaustive bibliographic searches through the Medline and Current Contents databases. CONTENT: A comprehensive table has been designed according to organic acids and conjugates. This table is intended to assist in the interpretation of organic acid profiles because, in addition to IEM, it also refers to other pathologic causes and to physiologic, nutritional, iatrogenic, and artifactual sources. Some preanalytical issues, including possible misinterpretations, are reviewed with regard to IEM. |
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Authors:
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Alain Kumps; Pierre Duez; Yves Mardens |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical chemistry Volume: 48 ISSN: 0009-9147 ISO Abbreviation: Clin. Chem. Publication Date: 2002 May |
Date Detail:
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Created Date: 2002-04-29 Completed Date: 2002-05-03 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9421549 Medline TA: Clin Chem Country: United States |
Other Details:
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Languages: eng Pagination: 708-17 Citation Subset: IM |
Affiliation:
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Laboratoire de Biochimie Médicale, Institut de Pharmacie, Université Libre de Bruxelles (ULB), Campus Plaine CP 205/3, Boulevard du Triomphe, B-1050 Brussels, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Artifacts* Blood Specimen Collection Carboxylic Acids / urine* Glycine / metabolism Humans Iatrogenic Disease* Metabolism, Inborn Errors / diagnosis* Nutritional Physiological Phenomena* |
| Chemical | |
Reg. No./Substance:
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0/Carboxylic Acids; 56-40-6/Glycine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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