Document Detail


Metabolic, nutritional, iatrogenic, and artifactual sources of urinary organic acids: a comprehensive table.
MedLine Citation:
PMID:  11978597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The determination of organic acids and glycine conjugates in urine is key for the diagnosis and follow-up of several inborn errors of metabolism (IEM). However, clinical interpretations may still be hindered by ambiguity in the sources of some urinary organic acids and acylglycines as well as in the relationship between their excretion and IEM. APPROACH: Relevant data have been compiled from major books and references on the topic and by exhaustive bibliographic searches through the Medline and Current Contents databases. CONTENT: A comprehensive table has been designed according to organic acids and conjugates. This table is intended to assist in the interpretation of organic acid profiles because, in addition to IEM, it also refers to other pathologic causes and to physiologic, nutritional, iatrogenic, and artifactual sources. Some preanalytical issues, including possible misinterpretations, are reviewed with regard to IEM.
Authors:
Alain Kumps; Pierre Duez; Yves Mardens
Related Documents :
7510737 - Effect of dietary salt restriction on urinary serotonin and 5-hydroxyindoleacetic acid ...
1970767 - Effect of microsomal enzyme inducers on biliary and urinary excretion of acetaminophen ...
3400977 - Urinary excretion of hmma and hva in infants.
6154967 - Urinary acid metabolites of biogenic amines in schizophrenic patients.
19795157 - Rna-amino acid binding: a stereochemical era for the genetic code.
6180677 - Stability of monoamine metabolites in human cerebrospinal fluid.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  48     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-04-29     Completed Date:  2002-05-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  708-17     Citation Subset:  IM    
Affiliation:
Laboratoire de Biochimie Médicale, Institut de Pharmacie, Université Libre de Bruxelles (ULB), Campus Plaine CP 205/3, Boulevard du Triomphe, B-1050 Brussels, Belgium.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Artifacts*
Blood Specimen Collection
Carboxylic Acids / urine*
Glycine / metabolism
Humans
Iatrogenic Disease*
Metabolism, Inborn Errors / diagnosis*
Nutritional Physiological Phenomena*
Chemical
Reg. No./Substance:
0/Carboxylic Acids; 56-40-6/Glycine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cystatin C: an improved estimator of glomerular filtration rate?
Next Document:  Use of constant denaturant capillary electrophoresis of pooled blood samples to identify single-nucl...