Document Detail


Metabolic management of ischaemic heart disease.
MedLine Citation:
PMID:  7904560     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present review summarizes the available information on the effects of the three major classes of antianginal agents (nitrates, calcium and beta-blockers) on myocardial energy metabolism. It also discusses the role of some new molecules (L-carnitine, trimetazidine and ranolazine) that have been proposed as an alternative pharmacological approach for the metabolic management of cardiac ischaemic syndromes.
Authors:
S L Chierchia; G Fragasso
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European heart journal     Volume:  14 Suppl G     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1994-02-24     Completed Date:  1994-02-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2-5     Citation Subset:  IM    
Affiliation:
Istituto Scientifico H San Raffaele, Milan, Italy.
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MeSH Terms
Descriptor/Qualifier:
Acetanilides
Adrenergic beta-Antagonists / therapeutic use*
Angina Pectoris / drug therapy*
Calcium Channel Blockers / therapeutic use*
Carnitine / therapeutic use
Energy Metabolism / drug effects
Humans
Myocardium / metabolism*
Nitroglycerin / therapeutic use*
Piperazines / therapeutic use
Trimetazidine / therapeutic use
Chemical
Reg. No./Substance:
0/Acetanilides; 0/Adrenergic beta-Antagonists; 0/Calcium Channel Blockers; 0/Piperazines; 110445-25-5/ranolazine; 5011-34-7/Trimetazidine; 541-15-1/Carnitine; 55-63-0/Nitroglycerin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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