Document Detail

Metabolic energy requirements during manned orbital Skylab missions.
MedLine Citation:
PMID:  11958214     Owner:  NASA     Status:  MEDLINE    
An investigation was undertaken to determine the metabolic cost of life in space. Energy intake was determined throughout the 28-, 59- and 84-day flights for each of the nine Skylab astronauts. Metabolic excretions were quantitatively collected and analyzed for a variety of biochemical constituents. Body mass was determined each day and body volume was ascertained by stereophotogrammetric means immediately pre- and post-flight. A ground-based control period of at least 3 weeks preceded each flight, and one of at least 18 days followed each flight. Examination of the data reveals that all crew members lost mass in flight, and that this loss did not result in a net increase in density. Elevated urinary and blood nitrogen, a net negative calcium and nitrogen balance and a decrease in the radiographic density of certain bones support the conclusion that lean body mass decreased. That the loss was primarily proteinaceous in nature is evidenced by the comparatively small net change in total body water and by a decrease in total body potassium each measured by isotopic dilution techniques. These changes in body composition, despite a constant caloric intake in flight and on the ground, suggest that the body's demand for exogenous nutrient energy is not measurably changed by exposure to null gravity flight up to 84 days in duration.
P C Rambaut; C S Leach; G D Whedon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Life sciences and space research     Volume:  15     ISSN:  0075-9422     ISO Abbreviation:  Life Sci Space Res     Publication Date:  1977  
Date Detail:
Created Date:  2002-04-16     Completed Date:  2002-10-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1250331     Medline TA:  Life Sci Space Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  187-91     Citation Subset:  S    
NASA-Johnson Space Center, Houston, Texas, USA.
Space Flight Mission:
Flight Experiment; Skylab 2 Project; Skylab 3 Project; Skylab 4 Project; long duration; manned; short duration
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MeSH Terms
Adaptation, Physiological*
Body Mass Index
Body Weight*
Calcium / metabolism
Carbon Dioxide / metabolism
Energy Metabolism*
Extracellular Space
Nitrogen / blood,  urine
Nutritional Requirements
Oxygen Consumption / physiology
Potassium / metabolism
Space Flight*
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7440-09-7/Potassium; 7440-70-2/Calcium; 7727-37-9/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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