Document Detail

Metabolic alterations in broiler chickens experimentally infected with sporulated oocysts of Eimeria maxima.
MedLine Citation:
PMID:  25271449     Owner:  NLM     Status:  In-Data-Review    
Metabolic and morphometric alterations of the duodenal villi caused by parasitism of chickens by Eimeria maxima were evaluated, using 100 male Cobb birds, randomly distributed into two groups (control and infected). The infected group was inoculated with 0.5 ml of a solution containing 5×103 sporulated oocysts of Eimeria maxima. Ten birds per sample were sacrificed on the 6th, 11th, 22nd and 41st days post-infection (dpi). In order to evaluate the alterations, samples of duodenum, jejunum and ileum fragments were collected after necropsy for histological analysis. Villus biometry was determined by means of a slide graduated in microns that was attached to a binocular microscope. To evaluate the biochemical data, 5 ml of blood were sampled from the birds before sacrifice. The statistical analyses were performed using the GraphPad 5 statistical software for Windows. Tukey's multiple comparison test (p <0.05) was performed for the different dpi's and the unpaired t test for the difference between the groups. Infection by E. maxima causes both qualitative and quantitative alterations to the structure of the intestinal villi, thereby interfering with the absorption of nutrients such as calcium, phosphorus, magnesium, protein and lipids, with consequent reductions in the birds' weights.
Fagner Luiz da Costa Freitas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária     Volume:  23     ISSN:  1984-2961     ISO Abbreviation:  Rev Bras Parasitol Vet     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-10-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440482     Medline TA:  Rev Bras Parasitol Vet     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  309-14     Citation Subset:  IM    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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