| Metabolic Syndrome in Obese Adolescents is Associated with Risk for Nephrolithiasis. | |
| | |
MedLine Citation:
|
PMID: 22099686 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVES: To examine the relationship between urinary pH and metabolic syndrome risk factors along with insulin resistance in obese adolescents, and to evaluate the relationship between other urinary stone-forming and -inhibiting markers and metabolic syndrome. STUDY DESIGN: A total of 46 obese adolescents were enrolled. Twenty-four hour and randomly obtained urine samples were analyzed for urinary pH, promoters of stone formation (ie, uric acid, oxalate, and relative saturation ratio of calcium oxalate [RSR-CaOx]), and inhibitors of stone formation (ie, citrate and osteopontin). Other data collected included height, weight, blood pressure, and fasting lipid, insulin, and glucose levels. RESULTS: The subjects had a mean age of 14.6±2.0 years and a mean body mass index of 36±6.3 kg/m(2). Random urine pH and the number of risk factors for metabolic syndrome were negatively correlated (r=-0.34; P=.02). RSR-CaOx was correlated with both homeostasis model assessment of insulin resistance score (r=0.38; P<.01) and number of risk factors for metabolic syndrome (r=0.47; P=.001) CONCLUSION: Decreased urinary pH and increased RSR-CaOx are associated with risk factors for metabolic syndrome in obese adolescents. |
| | |
Authors:
|
Rishita Tiwari; Thomas Campfield; Chrystal Wittcopp; Gregory Braden; Paul Visintainer; Edward O Reiter; Holley F Allen |
Related Documents
:
|
21950986 - Cerebellar ataxia, neuropathy, vestibular areflexia syndrome (canvas): a review of the ... 22003216 - Apparent dexmedetomidine-induced polyuric syndrome in an achondroplastic patient underg... 21721436 - Nephrotic syndrome in elderly patients: three years experience at siriraj hospital. 22227126 - The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glu... 987606 - The involvement of further nutritional factors in the fatty liver and kidney syndrome i... 4707236 - The co-existence of primary hyperparathyroidism and osteogenesis imperfecta. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-16 |
Journal Detail:
|
Title: The Journal of pediatrics Volume: - ISSN: 1097-6833 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-21 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Mosby, Inc. All rights reserved. |
Affiliation:
|
Department of Pediatrics, Baystate Medical Center/Tufts University School of Medicine and Tufts University School of Medicine, Boston, MA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Expanding the linear dynamic range for multiple reaction monitoring in quantitative liquid chromatog...
Next Document: 2009 Influenza A in Infants Hospitalized at Younger than 6 Months.