Document Detail


Metabolic syndrome and its association with colorectal cancer: a review.
MedLine Citation:
PMID:  20460980     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Currently, significant amount of epidemiologic evidence is present to suggest that metabolic syndrome increases the risk of developing colorectal cancer. This evidence is based on studies of the evaluate determinants of the metabolic syndrome (obesity), clinical consequences of metabolic syndrome (type 2 diabetes and hypertension) and serum component of metabolic syndrome (hypertriglyceridemia, hyperglycemia and low high-density lipoprotein cholesterol), as well as markers of hyperinsulinemia. Although the exact pathogenesis of this relationship is unknown, it seems that hyperinsulinemia may play a pivotal role in increasing CRC risk.
Authors:
Ali A Siddiqui
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  341     ISSN:  1538-2990     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  227-31     Citation Subset:  AIM; IM    
Affiliation:
From the Department of Internal Medicine, Dallas Veterans Affairs Medical Center, and Division of Gastroenterology and Hepatology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas. Submitted March 16, 2010; accepted in revised form March 24, 2010.
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