| Metabolic Syndrome, Androgens, and Hypertension. | |
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MedLine Citation:
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PMID: 21274756 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Obesity is one of the constellation of factors that make up the definition of the metabolic syndrome. Metabolic syndrome is also associated with insulin resistance, dyslipidemia, hypertriglyceridemia, and type 2 diabetes mellitus. The presence of obesity and metabolic syndrome in men and women is also associated with increased risk of cardiovascular disease and hypertension. In men, obesity and metabolic syndrome are associated with reductions in testosterone levels. In women, obesity and metabolic syndrome are associated with increases in androgen levels. In men, reductions in androgen levels are associated with inflammation, and androgen supplements reduce inflammation. In women, increases in androgens are associated with increases in inflammatory cytokines, and reducing androgens reduces inflammation. This review discusses the possibility that the effects of androgens on metabolic syndrome and its sequelae may differ between males and females. |
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Authors:
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Mohadetheh Moulana; Roberta Lima; Jane F Reckelhoff |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-29 |
Journal Detail:
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Title: Current hypertension reports Volume: - ISSN: 1534-3111 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-1-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888982 Medline TA: Curr Hypertens Rep Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Women's Health Research Center, University of Mississippi Medical Center, 2500 N. State Street, Jackson, MS, 39216-4505, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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