Document Detail


Metabolic effects of Roux-en-Y gastric bypass in obese adolescents and young adults.
MedLine Citation:
PMID:  23274343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Weight loss surgery is an increasingly common treatment option for obese adolescents, but data are limited regarding the metabolic effects of surgical weight loss procedures. We performed a retrospective review of the electronic medical record to determine metabolic outcomes for 24 adolescents and young adults ages 15 to 22 years undergoing Roux-en-Y gastric bypass from 2009 to 2011 as well as 24 age-, sex-, and BMI-matched controls. During a median follow-up of 6 months after Roux-en-Y gastric bypass, fasting glucose, hemoglobin A1c, low-density lipoprotein, triglyceride, and high-sensitivity C-reactive protein decreased significantly. Changes in these measures were not significantly associated with age or extent of weight loss.
Authors:
Manasi Sinha; Takara L Stanley; Jessica Webb; Christina Scirica; Kathleen Corey; Janey Pratt; Paul A Boepple; Alison Hoppin; Madhusmita Misra
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  56     ISSN:  1536-4801     ISO Abbreviation:  J. Pediatr. Gastroenterol. Nutr.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-25     Completed Date:  2013-11-01     Revised Date:  2014-05-07    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  528-31     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Glucose / metabolism*
Body Mass Index
C-Reactive Protein / metabolism*
Case-Control Studies
Cholesterol, LDL / blood
Female
Gastric Bypass*
Hemoglobin A, Glycosylated / metabolism*
Humans
Lipids / blood*
Male
Obesity / blood*,  surgery
Obesity, Morbid / blood,  surgery
Retrospective Studies
Triglycerides / blood
Weight Loss / physiology*
Young Adult
Grant Support
ID/Acronym/Agency:
K23 DK089910/DK/NIDDK NIH HHS; K23DK089910/DK/NIDDK NIH HHS; T32 HD052961/HD/NICHD NIH HHS; T32HD052961/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Cholesterol, LDL; 0/Hemoglobin A, Glycosylated; 0/Lipids; 0/Triglycerides; 9007-41-4/C-Reactive Protein
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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