| Meta-analysis of upper probe measurements in normal subjects and patients with laryngopharyngeal reflux. | |
| | |
MedLine Citation:
|
PMID: 15825565 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report a meta-analysis of a series of studies in which 24-hour ambulatory pH monitoring was performed in 1) normal subjects, 2) the normal control subjects in studies of laryngopharyngeal reflux (LPR), and 3) the patients with LPR in these controlled studies. The statistical analysis utilized the fixed-effects model by Mantel-Haenszel and the random-effects mixed model. There were 16 studies from the past 12 years that fulfilled the inclusion criteria. They involved 793 subjects (264 normal and 529 with LPR). The numbers of positive pharyngeal reflux events for normal subjects and for patients with LPR differed with a p value of <.0001. There was also a significant difference in the mean percentage of acid exposure times between normal subjects and patients with LPR (p = .003). We conclude that the upper probe gives accurate and consistent information in normal subjects and patients with LPR. The numbers of reflux events and acid exposure times are most important in distinguishing normal subjects from patients with LPR. The technology and methodology of probe testing is quite reliable and is consistent on a worldwide basis. |
| | |
Authors:
|
Albert L Merati; Hyun J Lim; Seckin O Ulualp; Robert J Toohill |
Related Documents
:
|
11215775 - Gastroesophageal reflux and diaphragmatic motility after repair of congenital diaphragm... 12109955 - Frustration and fulfillment of needs in dissociative and conversion disorders. 21304025 - A comparative look at the safety profiles of intravenous iron products used in the hemo... 8733455 - Speech assessment of patients using three types of indwelling tracheo-oesophageal voice... 8779455 - Piperacillin to prevent cholangitis after endoscopic retrograde cholangiopancreatograph... 6520805 - Type a and ectopy in patients with coronary artery disease and controls. |
Publication Detail:
|
Type: Journal Article; Meta-Analysis; Review |
Journal Detail:
|
Title: The Annals of otology, rhinology, and laryngology Volume: 114 ISSN: 0003-4894 ISO Abbreviation: Ann. Otol. Rhinol. Laryngol. Publication Date: 2005 Mar |
Date Detail:
|
Created Date: 2005-04-13 Completed Date: 2005-05-03 Revised Date: 2006-05-15 |
Medline Journal Info:
|
Nlm Unique ID: 0407300 Medline TA: Ann Otol Rhinol Laryngol Country: United States |
Other Details:
|
Languages: eng Pagination: 177-82 Citation Subset: AIM; IM |
Affiliation:
|
Department of Otolaryngology and Communication Sciences and the Division of Biostatistics, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226-0099, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Case-Control Studies Gastroesophageal Reflux / diagnosis* Humans Hydrogen-Ion Concentration Laryngeal Diseases / diagnosis* Laryngoscopy* Monitoring, Ambulatory / methods* Pharyngeal Diseases / diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Flexible endoscopic evaluation of swallowing with sensory testing: patient characteristics and analy...
Next Document: Histologic characterization of rat vocal fold scarring.