| Meta-analysis and systematic review of colorectal endoscopic mucosal resection. | |
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MedLine Citation:
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PMID: 19750569 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To evaluate the proportion of successful complete cure en-bloc resections of large colorectal polyps achieved by endoscopic mucosal resection (EMR). METHODS: Studies using the EMR technique to resect large colorectal polyps were selected. Successful complete cure en-bloc resection was defined as one piece margin-free polyp resection. Articles were searched for in Medline, Pubmed, and the Cochrane Control Trial Registry, among other sources. RESULTS: An initial search identified 2620 reference articles, from which 429 relevant articles were selected and reviewed. Data was extracted from 25 studies (n = 5221) which met the inclusion criteria. All the studies used snares to perform EMR. Pooled proportion of en-bloc resections using a random effect model was 62.85% (95% CI: 51.50-73.52). The pooled proportion for complete cure en-bloc resections using a random effect model was 58.66% (95% CI: 47.14-69.71). With higher patient load (> 200 patients), this complete cure en-bloc resection rate improves from 44.19% (95% CI: 24.31-65.09) to 69.17% (95% CI: 51.11-84.61). CONCLUSION: EMR is an effective technique for the resection of large colorectal polyps and offers an alternative to surgery. |
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Authors:
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Srinivas R Puli; Yasuo Kakugawa; Takuji Gotoda; Daphne Antillon; Yutaka Saito; Mainor R Antillon |
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Publication Detail:
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Type: Journal Article; Meta-Analysis; Review |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 15 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-09-14 Completed Date: 2009-09-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 4273-7 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology, University of Missouri-Columbia, Columbia, MO 65212, United States of America. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Colonic Polyps
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surgery* Colorectal Neoplasms / surgery* Endoscopy, Gastrointestinal* / statistics & numerical data Gastric Mucosa / surgery* Humans Precancerous Conditions / surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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