| Meta-analysis of pulmonary valve replacement after operative repair of tetralogy of fallot. | |
| | |
MedLine Citation:
|
PMID: 20691315 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The present meta-analysis aimed to determine the outcomes and effect on right ventricular (RV) function of surgical pulmonary valve replacement (PVR) in patients after repair of tetralogy of Fallot. The reported outcomes of surgical PVR in children and adults after tetralogy of Fallot repair were from relatively small observational studies. The PubMed database was searched from its inception to April 2009. Observational studies reporting on the following outcomes measures after surgical PVR were reviewed: early and late all-cause mortalities, the redo-PVR rate, and changes in the indexed RV volumes, ejection fraction, and QRS duration after PVR. Of the 305 citations screened, 15 met the criteria and were analyzed. The pooled early mortality rate (n = 595) was 2.1% (95% confidence interval [CI] 1.1% to 4.0%). The late mortality rate was 0.5%/patient-year (95% CI 0.2% to 0.8%/patient-year), and the redo-PVR rate was 1.9%/patient-year (95% CI 1.3% to 2.5%/patient-year). Data on RV volumes and ejection fractions were available from 5 studies (n = 141). The pooled mean difference in the indexed RV end-diastolic and end-systolic volume was -63 ml/m(2) (95% CI -55 to -72) and -37 ml/m(2) (95% CI -30 to -45), respectively. No significant changes in the pooled mean difference of the RV ejection fraction (95% CI -1% to 3%) or QRS duration (95% CI -10 to 1 ms) were observed. In conclusion, surgical PVR in patients after tetralogy of Fallot repair has been associated with low early and late mortality and significant decreases in RV volumes but no changes in the RV ejection fraction or QRS duration. |
| | |
Authors:
|
Eddie Wai-Yin Cheung; Wilfred Hang-Sang Wong; Yiu-Fai Cheung |
Related Documents
:
|
22372915 - Flexible ureterorenoscopy versus extracorporeal shock wave lithotripsy for treatment of... 19576275 - Uptake of permethrin from impregnated clothing. 12410855 - Effects of dual blockade of the renin-angiotensin system in primary proteinuric nephrop... 19152905 - Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: a s... 20085495 - In vivo parasitological measures of artemisinin susceptibility. 19898185 - Retrospective review of the efficacy of topical bromfenac (0.09%) as an adjunctive ther... |
Publication Detail:
|
Type: Journal Article; Meta-Analysis |
Journal Detail:
|
Title: The American journal of cardiology Volume: 106 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-08-09 Completed Date: 2010-09-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 552-7 Citation Subset: AIM; IM |
Affiliation:
|
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, People's Republic of China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Child Heart Valve Prosthesis Implantation* / mortality Humans Postoperative Period Pulmonary Valve / surgery* Stroke Volume Tetralogy of Fallot / surgery* Treatment Outcome Ventricular Dysfunction, Right / physiopathology Ventricular Function, Right / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Atrial Arrhythmias in Adult Patients With Right- Versus Left-Sided Congenital Heart Disease Anomalie...
Next Document: Outcome in Stable Patients With Acute Pulmonary Embolism Who Had Right Ventricular Enlargement and/o...