Document Detail

Mesotheliomas following exposure to asbestos used in railroads: 130 Italian cases.
MedLine Citation:
PMID:  8684297     Owner:  NLM     Status:  MEDLINE    
The available knowledge on the oncogenic risks of asbestos, the data on the uses of asbestos in railroads, with particular regard to the Italian State Railroads (Ferrovie dello Stato = FS), and the groups at risk due to the exposure to asbestos used in railroads were briefly reviewed. The available data on the pathological effects of such exposure, and particularly on the onset of mesotheliomas among machinists and other railroad workers, were also summarized. One hundred and thirty cases of mesothelioma (122 pleural, 1 pericardial, 6 peritoneal and 1 pleuro-peritoneal), related to the exposure to asbestos used in railroads, observed in various Italian regions, were reported. Fifty-three of these cases (among which 49 reported in the Emilia Romagna Region) were submitted to a detailed study at the Bologna Institute of Oncology. Seventy-seven cases of mesothelioma occurred among occupationally exposed FS workers, in particular machinists; 45 cases occurred among rolling-stock machinists and workers engaged in the repair and demolition of the rails of workshops not belonging to the FS; 3 cases occurred among travelling workers of rolling-stock, not belonging to the FS; and 5 cases were found in family members (1 daughter, 3 wives and 1 sister) of railroad workers. This series of cases, together with similar data from the literature, proves the existence of an actual health risk due to asbestos used in railroads, and indicates its gravity. On the basis of the available data, the following steps are considered necessary: the promotion of systematic epidemiological investigations, the adoption of preventive measures, the performance of medical oncological surveillance, and the automatic compensation for tumours following the exposure to the asbestos used in railroads.
C Maltoni; C Pinto; R Carnuccio; D Valenti; P Lodi; E Amaducci
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  La Medicina del lavoro     Volume:  86     ISSN:  0025-7818     ISO Abbreviation:  Med Lav     Publication Date:    1995 Sep-Oct
Date Detail:
Created Date:  1996-08-22     Completed Date:  1996-08-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401176     Medline TA:  Med Lav     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  461-77     Citation Subset:  IM    
European Ramazzini Foundation of Oncology and Evironmental Sciences, Bologna
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MeSH Terms
Asbestos / adverse effects*
Heart Neoplasms / etiology*
Lung Neoplasms / etiology*
Mesothelioma / etiology*
Middle Aged
Occupational Exposure*
Peritoneal Neoplasms / etiology*
Pleural Neoplasms / etiology*
Risk Factors
Time Factors
Reg. No./Substance:
Comment In:
Med Lav. 1996 May-Jun;87(3):268-9   [PMID:  8858903 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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