| Mesopic contrast sensitivity and ocular higher-order aberrations after overnight orthokeratology. | |
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MedLine Citation:
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PMID: 18241829 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To investigate mesopic contrast sensitivity and night driving ability in eyes undergoing overnight orthokeratology, and to analyze the relationship among mesopic contrast sensitivity, ocular higher-order aberrations, and myopic correction. DESIGN: Prospective, noncomparative, consecutive case series. METHODS: In 44 eyes of 22 subjects (mean age +/- standard deviation [SD], 24.0 +/- 3.2 years) with orthokeratology, ocular aberrations and mesopic contrast sensitivity were determined before and three months after commencement of the procedure. Mean spherical equivalent refraction +/- SD was -2.34 +/- 0.99 diopters at baseline. Mesopic contrast sensitivity with and without glare was assessed using the Mesotest II (Oculus, Wetzlar, Germany). RESULTS: Orthokeratology significantly reduced the log mesopic contrast sensitivity from 0.25 +/- 0.08 to 0.08 +/- 0.10 without glare (P < .0001, Wilcoxon) and from 0.21 +/- 0.11 to 0.07 +/- 0.10 with glare (P < .0001). The proportion of eyes that fulfilled the German standard recommendation level for night driving was 36%. The induced changes in log mesopic contrast sensitivity showed significant negative correlation with the changes in third-order (r = -0.490, P = .0013 without glare; r = -0.362, P = .0177 with glare; Spearman rank correlation coefficient) and fourth-order root mean square (r = -0.586, P = .0001 and r = -0.306, P = .0450, respectively). Furthermore, significant correlation was found between the amount of myopic correction and the induced changes in log mesopic contrast sensitivity (r = -0.442, P = .0038 without glare; r = -0.464, P = .0024 with glare). The induced changes in higher-order aberrations significantly correlated with the amount of myopic correction (P < .0001, Pearson correlation coefficient). CONCLUSIONS: Mesopic contrast sensitivity after overnight orthokeratology is deteriorated significantly as ocular higher-order aberrations increase, and these changes depend on the amount of myopic correction. |
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Authors:
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Takahiro Hiraoka; Chikako Okamoto; Yuko Ishii; Tomonori Takahira; Tetsuhiko Kakita; Tetsuro Oshika |
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Publication Detail:
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Type: Journal Article Date: 2008-02-01 |
Journal Detail:
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Title: American journal of ophthalmology Volume: 145 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-24 Completed Date: 2008-05-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 645-655 Citation Subset: AIM; IM |
Affiliation:
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Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan. thiraoka@md.tsukuba.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Automobile Driving Contrast Sensitivity* Dark Adaptation Female Glare Humans Male Myopia / therapy Orthokeratologic Procedures / adverse effects* Prospective Studies Refractive Errors / etiology* Vision Disorders / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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