Document Detail

Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype.
MedLine Citation:
PMID:  19000982     Owner:  NLM     Status:  MEDLINE    
The case of a 30-year-old man with bowel infarction due to mesenteric venous thrombosis and multiple risk factors, including mild hyperhomocysteinemia due to methylenetetrahydrofolate reductase C677T polymorphism and recent abdominal surgery, is reported. His clinical manifestation consisted of persistent abdominal pain; complementary examinations showed nonspecific findings such as leukocytosis and dilated loops of the bowel. The diagnosis of mesenteric venous thrombosis with bowel infarction was made during laparotomy and confirmed by anatomopathologic examination. He underwent segmental resection associated with lifelong anticoagulant therapy and vitamin B supplementation with a favorable course.
Cristina Hotoleanu; Octavian Andercou; Aurel Andercou
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Vascular and endovascular surgery     Volume:  42     ISSN:  1538-5744     ISO Abbreviation:  Vasc Endovascular Surg     Publication Date:    2008 Oct-Nov
Date Detail:
Created Date:  2008-11-12     Completed Date:  2009-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136421     Medline TA:  Vasc Endovascular Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  477-81     Citation Subset:  IM    
Medical Clinic, University of Medicine and Pharmacy, Cluj-Napoca, Romania.
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MeSH Terms
Abdominal Pain / genetics
Anticoagulants / therapeutic use
Digestive System Surgical Procedures
Hyperhomocysteinemia / complications,  enzymology,  genetics*,  therapy
Infarction / genetics*,  pathology,  therapy
Jejunum / blood supply*,  pathology,  surgery
Mesenteric Vascular Occlusion / diagnosis*,  genetics,  therapy
Mesenteric Veins
Methylenetetrahydrofolate Reductase (NADPH2) / genetics*
Treatment Outcome
Venous Thrombosis / diagnosis*,  genetics,  therapy
Vitamin B Complex / therapeutic use
Reg. No./Substance:
0/Anticoagulants; 12001-76-2/Vitamin B Complex; EC Reductase (NADPH2)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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