Document Detail

Mesenchymal hamartoma of the liver mimicking hepatoblastoma.
MedLine Citation:
PMID:  18525464     Owner:  NLM     Status:  MEDLINE    
Mesenchymal hamartoma of the liver is a cystic benign liver mass occurring in children. Diagnostic confusion with hepatoblastoma may arise when alpha-feto-protein (AFP) level is elevated. We report an extremely rare case of mesenchymal hamartoma in an 11-month-old boy. Serum AFP was elevated and fine-needle aspiration biopsy suggested the lesion as hepatoblastoma, so he received preoperative chemotherapy. At the end of the preoperative chemotherapy, the tumor size and AFP level decreased. A right hepatectomy was performed. The pathologic examination of the specimen revealed mesenchymal hamartoma. Mesenchymal hamartoma of the liver with increased serum AFP levels may mimic hepatoblastoma if a cytological examination samples only the hepatocellular component of mesenchymal hamartoma. According to our knowledge, this is the first case of the mesenchymal hamartoma of the liver, which showed reduction in serum levels of AFP and involution of the tumor size by preoperative chemotherapy.
Ekrem Unal; Yavuz Koksal; Zuhal Akcoren; Lema Tavl; Engin Gunel; Ulku Kerimoglu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  30     ISSN:  1077-4114     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-23     Completed Date:  2008-07-22     Revised Date:  2011-10-06    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  458-60     Citation Subset:  IM    
Department of Pediatrics, Selcuk University, Meram Faculty of Medicine, Konya, Turkey.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy, Fine-Needle
Diagnostic Errors*
Hamartoma / blood,  pathology*,  surgery
Hepatoblastoma / drug therapy,  pathology*
Liver Diseases / blood,  pathology*,  surgery
Liver Neoplasms / drug therapy,  pathology
Mesoderm / pathology
alpha-Fetoproteins / analysis*
Reg. No./Substance:

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