| Mesenchymal Stem Cell Treatment of Complications of Diabetes Mellitus. | |
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MedLine Citation:
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PMID: 21064114 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Mesenchymal stem cells (MSCs) are multipotent, self-renewing cells that can be found in almost all postnatal organs and tissues. The main functional characteristics of MSCs are their immunomodulatory ability, capacity for self-renewal and differentiation into mesodermal tissues. The ability of MSCs to differentiate into several cell types, including muscle, brain, vascular, skin, cartilage, and bone cells makes them attractive as therapeutic agents for a number of diseases including complications of diabetes mellitus. We review here the potential of MSCs as new therapeutic agents in the treatment of diabetic cardiomyopathy, diabetic nephropathy, diabetic polyneuropathy, diabetic retinopathy, and diabetic wounds. Also, in this review we discuss the current limitations for MSCs therapy in humans. |
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Authors:
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Vladislav Volarevic; Nebojsa Arsenijevic; Miodrag L Lukic; Miodrag Stojkovic |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-11-9 |
Journal Detail:
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Title: Stem cells (Dayton, Ohio) Volume: - ISSN: 1549-4918 ISO Abbreviation: - Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9304532 Medline TA: Stem Cells Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Centre for Molecular Medicine, Faculty of Medicine, University of Kragujevac, Serbia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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